Marginal corneal infiltrates - A possible new manifestation of sinus histiocytosis with massive lymphadenopathy

Purpose. To describe unilateral deep marginal corneal infiltrates and chron ic anterior uveitis in a young patient with sinus histiocytosis and massive lymphadenopathy. Methods, A 20-year-old man with a painless enlargement of his cervical lymph nodes was followed for five years after debulking of th ese nodes on the right side for right chronic anterior uveitis and deep mar ginal corneal infiltrates. Results. Histological sections of cervical lymph node confirmed the diagnosis of sinus histiocytosis with the typical emper ipolesis. The uveitis partially responded to topical corticosteroid treatme nt but tended to recur upon its withdrawal. The marginal corneal infiltrate s resolved gradually over a period of five years. Conclusions, Marginal cor neal infiltrates and uveitis may presumably be associated with sinus histio cytosis. Patients with sinus histiocytosis should also be screened for rare ocular involvement, such as uveitis and corneal infiltrates.