The influence of infections on the development and severity of allergic disorders

Authors
Herz, U Lacy, P Renz, H Erb, K
Citation
U. Herz et al., The influence of infections on the development and severity of allergic disorders, CURR OP IM, 12(6), 2000, pp. 632-640
Citations number
63
Categorie Soggetti
Immunology
Journal title
CURRENT OPINION IN IMMUNOLOGY
ISSN journal
09527915 → ACNP
Volume
12
Issue
6
Year of publication
2000
Pages
632 - 640
Database
ISI
SICI code
0952-7915(200012)12:6<632:TIOIOT>2.0.ZU;2-D
Abstract
The frequency and severity of atopic disorders are steadily increasing, par ticularly in developing countries. The reason for this observation is not c lear. Recent studies indicate that infections with viruses and especially w ith bacteria early in life may help to inhibit allergic Th2 responses by sk ewing the immune system towards Th1 responses. However, infections can also lead to the exacerbation of atopic disorders.