The origins of positron emission tomography (PET) dare back 70 years. Since
the 1970s, however, its use has increased exponentially in the fields of n
eurology, cardiology and oncology. [F-18]-Fluorodeoxyglucose (FDG) whole-bo
dy scanning is by far the most widely utilised and recognised application o
f PET in oncology. However, PET is a very versatile and powerful imaging mo
dality capable of helping bridge the gap between the laboratory and the cli
nic. This article reviews the history and current applications of PET in on
cology and then explores some of the newer applications and potential futur
e uses of this versatile technology particularly in the area of cancer rese
arch. (C) 2000 Elsevier Science Ltd. All rights reserved.