Imaging spectrum in sclerotic myelomas: an experience of three cases

The classis radiographic presentation of multiple myeloma is lytic skeletal lesions. Primary sclerotic manifestations are rare and occur only in 3% of cases. The imaging spectrum in three cases of multiple myeloma with primar y osteosclerosis is described. The first patient had spiculated sclerosis o f the orbit, which is an uncommon site for myeloma. The second patient with POEMS syndrome had multiple, scattered, skeletal lesions with sclerotic ma rgins. The third patient presented with a chest wall in the rib. The wide i maging spectrum possible in sclerotic myelomas and their relevant different ial diagnosis is emphasized.