A. Pirzkall et al., Conformal radiotherapy of challenging paraspinal tumors using a multiple arc segment technique, INT J RAD O, 48(4), 2000, pp. 1197-1204
Citations number
25
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Onconogenesis & Cancer Research
Journal title
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Purpose: Target volumes that wrap around the spinal cord are difficult to t
reat. We present and evaluate a refined multiple are segment (MAS) techniqu
e that is applicable with standard three-dimensional (3D) radiotherapy equi
pment and may be a solution for facilities that do not get have full access
to intensity-modulated radiotherapy (IMRT).
Methods and Materials: The presented technique consisted of 13 isocentric c
oplanar beam's eye view shaped fields,delivered as 20 degrees or 10 degrees
are segments with an integrated multileaf collimator (MLC) using automatic
sequential field delivery. Dose-volume histograms (DVH) for this technique
were compared to a modified bar-are technique (MBA) modeled as 30 static f
ields and to an inverse planned IMRT technique using 7 coplanar, equispaced
beams delivered with the same MLC.
Results: Compared to the MBA technique, maximum dose and target coverage we
re similar when using 80% of the maximum dose as the reference dose. Howeve
r, the MAS technique reduced the maximum doses (to greater than or equal to
1% of the organs at risk [OAR]) by 9% for the spinal cord, 17% for the esop
hagus, and 25% for the trachea, as well as the mean doses. Although inverse
planned IMRT could further reduce exposure of OAR except for the spinal co
rd and improve target coverage, our forward planned MAS technique seems to
achieve clinically comparable results.
Conclusion: Substituting a series of small split-field are segments for lar
ge static fields and using additional narrow paraspinal segments significan
tly improves the sparing of organs at risk for paraspinal targets, Although
these results are not quite as good as those achieved with IMRT, for facil
ities not yet equipped with inverse treatment planning capability, the pres
ented technique enables dose escalation for primary paraspinal tumors and r
etreatment of recurrent lesions, (C) 2000 Elsevier Science Inc.