Analysis of polycyclic aromatic hydrocarbons, phenols and aromatic amines in particulate phase cigarette smoke using simultaneous distillation and extraction as a sole sample clean-up step

Polycyclic aromatic hydrocarbons (PAHs), phenols and aromatic amines can be analyzed in particulate phase mainstream cigarette smoke using simultaneou s distillation and extraction (SDE) as a unique sample clean-up step. All a nalytes are determined from the same smoke sample using GC-MS. The smoke fr om 20 cigarettes is collected on a Cambridge smoke pad where a mixture of i nternal standards is added. The Cambridge smoke pad is extracted in a SDE a pparatus using water-CH2Cl2. The SDE extract is analyzed directly for PAHs, for phenols after silylation, and for amines after derivatization with hep tafluorobutyric anhydride. Excellent results in agreement with data reporte d in the literature are obtained by this procedure. (C) 2000 Elsevier Scien ce B.V. All rights reserved.