Background: We report a case of a palisaded angioleiomyoma, a histopatholog
ic variant of angioleiomyoma with prominent Verocay body formation.
Results: A healthy 31-year-old male requested removal of a subcutaneous nod
ule on the back of his head. The striking Verocay-like body formation of th
is tumor led to an initial frozen section diagnosis of neurilemoma. On hema
toxylin and eosin staining, areas consistent with an angioleiomyoma were fo
und as well. Immunohistochemistry gave positive reactions for actin and des
min, but was negative for S-100.
Conclusions: To our knowledge this morphologic pattern in an angioleiomyoma
has not been previously described. Palisaded angioleiomyoma should be adde
d to the ever-expanding list of tumors that demonstrate nuclear palisades.
(C) Munksgaard 2000.