Bf. Don et al., Hydroxychloroquine retinopathy despite regular ophthalmologic evaluation: A consecutive series, J RHEUMATOL, 27(11), 2000, pp. 2703-2706
We describe a consecutive series of patients with hydroxychloroquine (HCQ)
retinopathy. Their clinical features illustrate that with normal renal func
tion there is no threshold for total dosage for HCQ toxicity; that color vi
sion testing is important; that almost all patients complain of altered cen
tral vision as their first symptom; and that a normal optic fundus does not
exclude the diagnosis. Finally, HCQ retinopathy may progress even when the
agent is stopped.