Papular-purpuric gloves and socks syndrome in HIV-positive patients

Three HIV-positive women showed clinical signs of papular-purpuric gloves a nd socks syndrome and serologic evidence of acute Parvovirus B19 infection. The course of the disease was complicated by anemia and persistent skin le sions, probably related to inadequate immune response. Because anemia in AI DS patients may be due to many causes, the history of recent Parvovirus B19 infection is helpful in suggesting the etiologic diagnosis.