Jd. Friedlander et al., FETAL BRADYCARDIA AND UTERINE HYPERACTIVITY FOLLOWING SUBARACHNOID ADMINISTRATION OF FENTANYL DURING LABOR - CASE-REPORT, Regional anesthesia, 22(4), 1997, pp. 378-381
Background and Objectives. Changes in uterine tone have been postulate
d as the cause of fetal bradycardia following subarachnoid administrat
ion of fentanyl for labor analgesia. Such a case occurred in a 20-year
-old parturient with an intrauterine pressure catheter in place. Metho
ds. The patient was given intravenous terbutaline, after which contrac
tions ceased for 20-30 minutes and then resumed. Results. The patient
underwent successful cesarean delivery. Retrospective analysis of the
data revealed a significant increase in uterine tone and contractions
following fentanyl administration. Conclusions. This case supports the
view that changes in uterine tone, producing a hyperdynamic contracti
le state and a resulting decrease in uteroplacental perfusion, may exp
lain the fetal bradycardia following subarachnoid opioid administratio
n. Cases that do not resolve spontaneously may respond to intravenous
terbutaline.