Cyclin' on the viral path to destruction

Authors
Hardwick, JM
Citation
Jm. Hardwick, Cyclin' on the viral path to destruction, NAT CELL BI, 2(11), 2000, pp. E203-E204
Citations number
13
Categorie Soggetti
Cell & Developmental Biology
Journal title
NATURE CELL BIOLOGY
ISSN journal
14657392 → ACNP
Volume
2
Issue
11
Year of publication
2000
Pages
E203 - E204
Database
ISI
SICI code
1465-7392(200011)2:11<E203:COTVPT>2.0.ZU;2-U
Abstract
Viruses are the masters of trickery. They mimic, manipulate and usurp cellu lar functions, hut always with an interesting twist. gamma -herpesvirus gen omes encode an abundance of homologues of cellular factors, including cycli n and Bcl-2. These viral homologues differ from their cellular counterparts in that the viral proteins have gained new functions and eliminated others to harness the cell and benefit the virus.