WEGENERS GRANULOMATOSIS IN PREGNANCY

This report describes a case of severe limited Wegener's granulomatosi s (WG) presenting in the third trimester of pregnancy with pansinusiti s and necrotizing pneumonitis. The patient was treated successfully wi th a combination of corticosteroids and cyclophosphamide (CYC). The ou tcomes in the mother and the newborn were excellent. In a review of th e English-language literature, we found 10 similar cases of WG with 13 pregnancies, WG occurring during pregnancy may have a more aggressive course and may require more aggressive treatment compared with WG occ urring at other times. The treatment options for WG in pregnancy are d iscussed.