The confused patient sitting across from you presents a number of diagnosti
c challenges. The range of explanations for confusion is daunting, to say t
he least. It could be a symptom of delirium, depression, dementia, or senso
ry deprivation, and each of these conditions has numerous causes that could
require substantial investigation, Dr Bostwick uses four scenarios involvi
ng a single patient, Mr S, to highlight the roles of physical and laborator
y examination, collateral history, and clarification of time course in maki
ng sense of the syndrome of confusion.