Si. Kawachi et al., SPONTANEOUS HEALING OF PANCREATIC-ABSCESS AFTER FISTULIZATION TO THE DUODENAL BULB, The American journal of the medical sciences, 314(1), 1997, pp. 44-46
A 70-year-old man was admitted to the hospital because of sudden, uppe
r abdominal and back pain. Laboratory and image data indicated acute p
ancreatitis, Shortly after the admission, pancreatic and liver abscess
with bacteremia developed. Antibiotic therapy seemed effective. A mon
th later, spontaneous fistulization of the pancreatic abscess to the d
uodenal bulb was found by gastroduodenal fiberscopy. Injection of cont
rast medium into the duodenal orifice showed that the fistula was drai
ning the abscess and that no other fistula formed from the abscess. En
doscopic retrograde cholangiopancreatogram indicated no fistula format
ion to the pancreatic duct. The pancreatic abscess became smaller and
was not visible using computerized tomography and ultrasonography 3 mo
nths later and thereafter. Closure of the duodenal orifice was ascerta
ined by the endoscopy. It is suggested that retrograde infection from
the fistula was prevented by the single fistulization to the acidic du
odenal bulb, which is not supposed to allow most bacterial growth. Pan
creatic abscess usually necessitates operative treatment, even with fi
stulization to the alimentary tract. It seems likely that the single,
small fistulization to the bulb, in addition to the lack of underlying
disease and medical and nutritional support, facilitated the spontane
ous healing process.