The genetic legacy of paleolithic Homo sapiens sapiens in extant Europeans: A Y chromosome perspective

Authors
Semino, O Passarino, G Oefner, PJ Lin, AA Arbuzova, S Beckman, LE De Benedictis, G Francalacci, P Kouvatsi, A Limborska, S Marcikiae, M Mika, A Mika, B Primorac, D Santachiara-Benerecetti, AS Cavalli-Sforza, LL Underhill, PA
Citation
O. Semino et al., The genetic legacy of paleolithic Homo sapiens sapiens in extant Europeans: A Y chromosome perspective, SCIENCE, 290(5494), 2000, pp. 1155-1159
Citations number
32
Categorie Soggetti
Multidisciplinary,Multidisciplinary,Multidisciplinary
Journal title
SCIENCE
ISSN journal
00368075 → ACNP
Volume
290
Issue
5494
Year of publication
2000
Pages
1155 - 1159
Database
ISI
SICI code
0036-8075(20001110)290:5494<1155:TGLOPH>2.0.ZU;2-3
Abstract
A genetic perspective of human history in Europe was derived from 22 binary markers of the nonrecombining Y chromosome (NRY). Ten lineages account for >95% of the 1007 European Y chromosomes studied. Geographic distribution a nd age estimates of alleles are compatible with two Paleolithic and one Neo lithic migratory episode that have contributed to the modern European gene pool. A significant correlation between the NRY haplotype data and principa l components based on 95 protein markers was observed, indicating the effec tiveness of NRY binary polymorphisms in the characterization of human popul ation composition and history.