The Baylis-Hillman reaction: One-pot stereoselective synthesis of methyl (2E)-3-aryl-2-hydroxymethylprop-2-enoates

Authors
Basavaiah, D Padmaja, K Satyanarayana, T
Citation
D. Basavaiah et al., The Baylis-Hillman reaction: One-pot stereoselective synthesis of methyl (2E)-3-aryl-2-hydroxymethylprop-2-enoates, SYNTHESIS-S, (12), 2000, pp. 1662-1664
Citations number
26
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
12
Year of publication
2000
Pages
1662 - 1664
Database
ISI
SICI code
0039-7881(200011):12<1662:TBROSS>2.0.ZU;2-Y
Abstract
A facile, simple and one-pot conversion of methyl 3-aryl-3-hydroxy-2-methyl enepropanoates into methyl (2E)-3-aryl-2-hydroxymethylprop-2-enoates via th e sequential treatment with acetic anhydride/teimethylsilyl trifluoromethan esulfonate (TMSOTf) and potassium carbonate/methanol is described.