Development of a catalytic cycle for the generation of C1-glycosyl carbanions with Cp2TiCl2: application to glycal synthesis

Authors
Hansen, T Daasbjerg, K Skrydstrup, T
Citation
T. Hansen et al., Development of a catalytic cycle for the generation of C1-glycosyl carbanions with Cp2TiCl2: application to glycal synthesis, TETRAHEDR L, 41(44), 2000, pp. 8645-8649
Citations number
28
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
44
Year of publication
2000
Pages
8645 - 8649
Database
ISI
SICI code
0040-4039(20001028)41:44<8645:DOACCF>2.0.ZU;2-W
Abstract
A catalytic cycle has been developed for the conversion of glycosyl halides to their corresponding glycals using Cp2TiCl2. This process can be effecti vely used with only 30% of the in situ generated single electron reducing a gent in contrast to the 2 equivalents normally employed. (C) 2000 Published by Elsevier Science Ltd.