Squamous cell carcinoma of the nasal planum in 17 dogs

Citation
Bdx. Lascelles et al., Squamous cell carcinoma of the nasal planum in 17 dogs, VET REC, 147(17), 2000, pp. 473-476
Citations number
17
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
VETERINARY RECORD
ISSN journal
00424900 → ACNP
Volume
147
Issue
17
Year of publication
2000
Pages
473 - 476
Database
ISI
SICI code
0042-4900(20001021)147:17<473:SCCOTN>2.0.ZU;2-8
Abstract
Squamous cell carcinoma of the nasal planum was diagnosed in 17 dogs over a period of 11 years. Ulceration, bleeding and sneezing were the most common clinical signs. One dog had cytological evidence of metastasis to the loca l lymph node. The dogs were treated by surgical resection, fractionated meg avoltage irradiation, or a combination of the two. Surgical resection gave the most favourable results; four of six dogs were cured but a recurrence o f the tumour was predicted in the other two on the basis of incomplete or m arginal resection. Radiotherapy alone was not as effective; one of four dog s was cured, and the tumour recurred in the others within 24 weeks (median eight weeks). Combined surgical resection and radiotherapy did not produce a cure in any of the seven remaining dogs, and the tumour recurred within 1 2 weeks (median nine weeks). Three dogs had cytological evidence of lymph n ode metastasis when the tumour recurred. The dogs' prognosis was adversely affected by the interval between their initial examination and treatment, b ut there was no apparent association between the histological grade of the tumour and the clinical outcome.