The advent of permanent hemodialysis access has made possible the use of ch
ronic hemodialysis in patients with endstage renal disease. Although autoge
nous arteriovenous fistulae remain the conduit of choice, their constructio
n is not always:feasible. Prosthetic grafts made of polytetrafluoroethylene
(PTFE) are typically the second-line choice for hemoaccess. However, these
grafts suffer from decreased rates of patency and an increased number of c
omplications. Although thrombosis is the most common complication, infectio
n of PTFE grafts accounts for a significant number of hospitalizations and
uses a large amount of healthcare resources. In this monograph, we address
infectious complications of PTFE hemoaccess grafts and present a review of
the recent literature.