Structure and expression of the human glycosylphosphatidylinositol phospholipase D1 (GPLD1) gene

Authors
Schofield, JN Rademacher, TW
Citation
Jn. Schofield et Tw. Rademacher, Structure and expression of the human glycosylphosphatidylinositol phospholipase D1 (GPLD1) gene, BBA-GENE ST, 1494(1-2), 2000, pp. 189-194
Citations number
23
Categorie Soggetti
Molecular Biology & Genetics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
ISSN journal
01674781 → ACNP
Volume
1494
Issue
1-2
Year of publication
2000
Pages
189 - 194
Database
ISI
SICI code
0167-4781(20001115)1494:1-2<189:SAEOTH>2.0.ZU;2-6
Abstract
Here we report the structure of the human glycosylphosphatidylinositol phos pholipase DI gene, which covers at least 80 kb on chromosome 6p22. The gene comprises 25 exons and encodes a 5.8 kb mRNA, which was detected only in t he liver. Southern blot analysis shows that the human genome contains only one GPLD gene and we could only detect one of the two previously reported c DNAs. (C) 2000 Elsevier Science B.V. All rights reserved.