Background: Individuals with lower socioeconomic status report greater expo
sure ro stressful life events and a greater impact of these events on their
lives than individuals with higher socioeconomic status, and this relation
ship between socioeconomic status and health begins at the earliest stages
of life. To extend on these results, we performed a psychoneuroendocrine st
udy of 217 children and 139 mothers.
Methods: Salivary cortisol levels and cognitive function were assessed in c
hildren, and a semistructured phone interview measuring symptoms of stress
and depression was conducted with their mothers.
Results: Children with low socioeconomic status present significantly,highe
r salivary cortisol levels than children with high socioeconomic status, an
d this socioeconomic status effect emerges as early as age 6, We also repor
t that a child's cortisol level is significantly correlated with his or her
mother's extent of depressive symptomatology.
Conclusions: These results offer a neurobiological determinant to the well-
known association between socioeconomic status and health that begins early
in life. (C) 2000 Society of Biological Psychiatry.