Solid-phase synthesis of di- and tripeptidic hydroxamic acids as inhibitors of procollagen C-proteinase

Authors
Dankwardt, SM Billedeau, RJ Lawley, LK Abbot, SC Martin, RL Chan, CS Van Wart, HE Walker, KAM
Citation
Sm. Dankwardt et al., Solid-phase synthesis of di- and tripeptidic hydroxamic acids as inhibitors of procollagen C-proteinase, BIOORG MED, 10(22), 2000, pp. 2513-2516
Citations number
4
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
22
Year of publication
2000
Pages
2513 - 2516
Database
ISI
SICI code
0960-894X(20001120)10:22<2513:SSODAT>2.0.ZU;2-E
Abstract
A solid-phase approach to the rapid synthesis of di- and tripeptide-like hy droxamic acids is presented. These compounds are shown to be potent inhibit ors of procollagen C-proteinase (PCP). (C) 2000 Elsevier Science Ltd. All r ights reserved.