Purpose: Over the past 30 years there have been experimental efforts at cat
heter-based management of aortic valve regurgitation with the idea of exten
ding treatment to nonsurgical candidates. A new catheter-based aortic valve
design is described.
Methods: The new catheter-delivered valve consists of a stent-based valve c
age with locking mechanism and a prosthetic flexible tilting Valve disc. Th
e valve cage is delivered first followed by deployment and locking of the d
isc. In acute experiments, valve implantation was done in four dogs.
Results: Valve implantation was successful in all four animals. The implant
ed valve functioned well for the duration of the experiments (up to 3 hr).
Conclusion: The study showed the implantation feasibility and short-term fu
nction of the tested catheter-based aortic disc valve. Further experimental
studies are warranted.