This review deals with the distribution of fluoride tolerance between algae
and cyanobacteria, their physiological response differences, and possible
mechanisms of action of fluoride in these groups. Algae and cyanobacteria d
iffer in their response to fluoride, the latter being more sensitive to flu
oride toxicity. The threshold concentration at which toxicity is manifested
varies between organisms and is pH dependent. Being a strong hydrogen bond
ing species fluoride is capable of interacting with most of the cellular co
mponents and thus has a plethora of effects on cell metabolism.