High throughput screening of gene expression signatures

Citation
A. Kuklin et al., High throughput screening of gene expression signatures, GENETICA, 108(1), 2000, pp. 41-46
Citations number
7
Categorie Soggetti
Molecular Biology & Genetics
Journal title
GENETICA
ISSN journal
00166707 → ACNP
Volume
108
Issue
1
Year of publication
2000
Pages
41 - 46
Database
ISI
SICI code
0016-6707(2000)108:1<41:HTSOGE>2.0.ZU;2-#
Abstract
This paper focuses on microarray image analysis and discusses a completely automated approach to image processing, which eliminates human intervention . A system for automated image processing is described, which is capable of processing image files in a batch-mode thus allowing high-throughput of mi croarray image analysis. Grid-placement and spot finding are achieved witho ut operator's help. The software eliminates noise signals from the data ana lysis process and minimizes operator's involvement in the procedure.