The accuracy of digital Roentgen stereophotogrammetric analysis (RSA) was c
ompared to the accuracy of a manually operated RSA system. For this purpose
, we used radiographs of a phantom and radiographs of patients. The radiogr
aphs of the patients consisted of double examinations of 12 patients that h
ad a tibial osteotomy and of double examinations of 12 patients that receiv
ed a total hip prosthesis. First, the radiographs were measured manually wi
th an accurate measurement table. Subsequently, the images were digitized b
y a film scanner at 150 DPI and 300 DPI resolutions and analyzed with the R
SA-CMS software. In the phantom experiment, the manually operated system pr
oduced significantly better results than the digital system, although the m
aximum difference between the median values of the manually operated system
and the digital system was as low as 0.013 mm for translations and 0.033 d
egrees for rotations. In the radiographs of the patients, the manually oper
ated system and the digital system produced equally accurate results: no si
gnificant differences in translations and rotations were found. We conclude
that digital RSA is an accurate, fast, and user friendly alternative for m
anually operated RSA. Currently, digital RSA systems are being used in a gr
owing number of clinical RSA-studies. (C) 2000 Elsevier Science Ltd. All ri
ghts reserved.