We have determined Y-chromosomal DNA haplotypes in 73 infertile European ma
les carrying Y microdeletions and compared them with the haplotypes of 299
infertile males lacking microdeletions. Chromosomes were typed with a set o
f 11 binary Y markers, which identified 8 haplogroups in the sample. Haplog
roup frequencies were compared between 3 microdeletion classes and the non-
deleted infertile males. Deletions arise on many different haplotypic backg
rounds. No statistically significant differences in frequency were seen, al
though the small number of AZFa deletions lay predominantly on one branch o
f the Y haplotype tree.(C) 2000, Editrice Kurtis.