Lg. Harshman et Ba. Haberer, Oxidative stress resistance: A robust correlated response to selection in extended longevity lines of Drosophila melanogaster?, J GERONT A, 55(9), 2000, pp. B415-B417
Citations number
19
Categorie Soggetti
Public Health & Health Care Science","Medical Research General Topics
Journal title
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
Stress resistance Is associated with longevity in Drosophila melanogaster a
cid other model organisms used for genetic research. The present study test
s for oxidative stress resistance in one set of lines selected for late-lif
e reproduction and extended longevity. Both females and males from the sele
cted lines were appreciably more resistant to oxidative stress than were fl
ies from the control lines. A relative increase in oxidative stress resista
nce is a correlated response to selection in this laboratory selection expe
riment. Increased oxidative stress resistance appears to be a relatively ro
bust correlated response to laboratory selection for late-life reproduction
and extended longevity.