EVALUATION OF SM-153-DIETHYLENETRIAMINEPENTAACETIC ACID FOR RADIOLABELING OF PHARMACEUTICAL DOSAGE FORMS BY NEUTRON-ACTIVATION

Authors
AWANG MB HARDY JG DAVIS SS PIMM MV PARRY SJ WILDING IR
Citation
Mb. Awang et al., EVALUATION OF SM-153-DIETHYLENETRIAMINEPENTAACETIC ACID FOR RADIOLABELING OF PHARMACEUTICAL DOSAGE FORMS BY NEUTRON-ACTIVATION, Nuclear medicine and biology, 21(7), 1994, pp. 905-909
Citations number
25
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
Nuclear medicine and biology
ISSN journal
09698051 → ACNP
Volume
21
Issue
7
Year of publication
1994
Pages
905 - 909
Database
ISI
SICI code
0969-8051(1994)21:7<905:EOSAFR>2.0.ZU;2-I
Abstract
Sm-153-DTPA provides a suitable alternative to Tc-99m-DTPA and In-111- DTPA as a water soluble tracer for the evaluation of pharmaceutical pr eparations. The chelate was handled biologically in a similar way to T c-99m-DTPA and In-111-DTPA. The chelate can be incorporated into the f ormulation as a non-radioactive excipient and the intact dosage form c an then be neutron activated to produce Sm-153.