Re. Shefer et al., A WINDOWLESS N-13 PRODUCTION TARGET FOR USE WITH LOW-ENERGY DEUTERON ACCELERATORS, Nuclear medicine and biology, 21(7), 1994, pp. 977-986
The recent development of low energy accelerators for positron emissio
n tomography has necessitated the development of new targets for N-13
production. C-12(d,n)N-13 reaction yields in graphite at low deuteron
beam energies (0.8-3.2 MeV) are presented and a new technique for the
in situ extraction of N-13 activity from solid graphite and subsequent
conversion to [N-13] ammonia is described. The target is windowless a
nd is reusable for multiple isotope production runs. This technique ut
ilizes radio frequency induction heating to rapidly heat the graphite
to combustion temperatures in an O-2 gas stream. The conversion of act
ivity induced in the target to [N-13] ammonia in under 10 min with an
overall decay-corrected efficiency of 45% is reported.