Glomerulocystic kidney disease following haemolytic-uraemic syndrome: Clinicopathological observation

Glomerulocystic kidney is a heterogeneous group of conditions morphological ly characterised by multiple cortical cysts apparently originated from a cy stic dilation of the filtration space with atrophy of the glomerular tufts. We report a case of glomerulocystic kidney affecting a 13-year-old boy who underwent renal transplantation for end-stage renal disease following a ha emolytic-uraemic syndrome diagnosed nine years ago.: The absence of other s tigmas (urinary obstruction, extrarenal congenital abnormalities and family history of cystic kidney disease) suggest that our observation is apparent ly a sporadic and acquired glomerulocystic kidney following a haemolytic-ur aemic syndrome, an infrequent association previously reported only twice. O ur histological and immunohistochemical findings suggest that the cysts in this rare condition are really of glomerular origin but the pathogenesis of cyst development remains unknown.