F. Vera-sempere et al., Glomerulocystic kidney disease following haemolytic-uraemic syndrome: Clinicopathological observation, NEFROLOGIA, 20(5), 2000, pp. 459-463
Glomerulocystic kidney is a heterogeneous group of conditions morphological
ly characterised by multiple cortical cysts apparently originated from a cy
stic dilation of the filtration space with atrophy of the glomerular tufts.
We report a case of glomerulocystic kidney affecting a 13-year-old boy who
underwent renal transplantation for end-stage renal disease following a ha
emolytic-uraemic syndrome diagnosed nine years ago.: The absence of other s
tigmas (urinary obstruction, extrarenal congenital abnormalities and family
history of cystic kidney disease) suggest that our observation is apparent
ly a sporadic and acquired glomerulocystic kidney following a haemolytic-ur
aemic syndrome, an infrequent association previously reported only twice. O
ur histological and immunohistochemical findings suggest that the cysts in
this rare condition are really of glomerular origin but the pathogenesis of
cyst development remains unknown.