The tear stability and tear volume of 55 asymptomatic Hong Kong-Chinese wer
e assessed before soft contact lens (Hydron Zero 6) wear and repeated on th
ree visits over 28 weeks of lens wear. Soft lens wear caused a significant
initial transient decrease in the non-invasive tear break-up time (NITBUT),
but no change in tear volume as assessed by the self-prepared cotton threa
d test (SP-CTT) and phenol red thread (PRT) test. After 28 weeks, the subje
cts were classified according to the length of time they could wear their l
enses without dry eye related signs and symptoms. The NITBUT and PRT tests
were unable to predict the success of soft contact lens wear. However, the
SP-CTT gave a sensitivity and specificity of 88.5 and 52.4%, respectively,
in the prediction of subjects most likely to be successful wearers. The pos
itive and negative predictive values at the chosen cut-off point were 69.7
and 78.6%, respectively. Wetting values, that is, combinations of NITBUT an
d SP-CTT values or NITBUT and PRT values, did not predict success in soft c
ontact lens wear. (C) 2000 The College of Optometrists. Published by Elsevi
er Science Ltd. All rights reserved.