Collagen vascular diseases: Cutaneous manifestations in ophthalmology

Purpose: To describe the effects of collagen vascular diseases on the eyeli ds and periorbital tissues. Methods: Retrospective review of dermatologic pathology slides at Massachus etts General Hospital and eye pathology slides at Massachusetts Eye and Ear Infirmary, Boston, Massachusetts. Results: A spectrum of dermatologic manifestations of collagen vascular dis eases was observed, affecting the eyelids and periorbital region. Conclusions: Collagen vascular diseases may present complicated diagnostic and clinical challenges for the practicing ophthalmologist. Familiarity wit h the cutaneous periocular manifestations of these diseases may facilitate early recognition, diagnosis, and ophthalmologic intervention where necessa ry.