We describe a case of focal argyrosis of the conjunctiva clinically simulat
ing a melanoma. An 82-year-old woman was referred for an asymptomatic pigme
nted conjunctival lesion. Her only significant past ocular history was stra
bismus surgery 76 years earlier. Biopsy of the conjunctiva and lateral rect
us muscle revealed the discoloration was pigment granules. Energy-dispersiv
e x-ray microanalysis revealed the pigmentation to be silver deposits. The
patient had strabismus surgery probably using a silver clip. Argyrosis shou
ld be considered in the differential diagnosis of focal pigmented conjuncti
val lesions.