Synthesis and application of planar-chiral phosphaferrocene-oxazolines, a new class of P,N-ligands

Authors
Shintani, R Lo, MMC Fu, GC
Citation
R. Shintani et al., Synthesis and application of planar-chiral phosphaferrocene-oxazolines, a new class of P,N-ligands, ORG LETT, 2(23), 2000, pp. 3695-3697
Citations number
26
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
23
Year of publication
2000
Pages
3695 - 3697
Database
ISI
SICI code
1523-7060(20001116)2:23<3695:SAAOPP>2.0.ZU;2-C
Abstract
[GRAPHICS] The synthesis of several phosphaferrocene-oxazolines, members of a new fami ly of planar-chiral ligands, is described. These bidentate P,N-ligands are applied to enantioselective palladium-catalyzed allylic alkylations, for wh ich it is shown that the planar-chirality of the phosphaferrocene, not the chirality of the oxazoline, determines the stereochemical outcome of the re action.