Aspirin is a widely used drug and perceived by most physicians to be inexpe
nsive. High rates of concurrent gastroprotective agents are reported from a
study of cardiology outpatients. Aspirin takers are more likely to also be
taking a proton pump inhibitor, H-2 antagonist, or antacid than non-aspiri
n takers. They are more than 10 times as likely to be experiencing upper ga
strointestinal symptoms. Although aspirin is inexpensive, it is emphasised
that the overall cost implications for therapy can be significant and it is
suggested that it may be more appropriate to consider the use of alternati
ve antiplatelet agents in patients who tolerate aspirin poorly.