Assessing patient outcomes in acute exacerbations of chronic bronchitis: The measure your medical outcome profile (MYMOP), medical outcomes study 6-item general health survey (MOS-6A) and EuroQol (EQ-5D)
C. Paterson et al., Assessing patient outcomes in acute exacerbations of chronic bronchitis: The measure your medical outcome profile (MYMOP), medical outcomes study 6-item general health survey (MOS-6A) and EuroQol (EQ-5D), QUAL LIFE R, 9(5), 2000, pp. 521-527
There is little published information on the measurement of health status o
r quality of life in acute exacerbations of chronic bronchitis. The measure
yourself medical outcome profile (MYMOP), the medical outcomes study 6-ite
m general health survey (MOS-6A), and EuroQoL (EQ-5D) were evaluated in 81
patients with acute exacerbations of Type-1 chronic bronchitis presenting a
t a single general practice centre in Glasgow. The questionnaires were admi
nistered at the first clinic visit and at a second visit within 1 week of t
reatment completion. Item scores for MYMOP were generally more responsive t
han those for the other instruments, as assessed by standardised response m
eans and an index of responsiveness for those patients reporting minimal ch
ange between visits. Construct validity was demonstrated for the MYMOP by t
he gradient in score change with the patient's perceived change in clinical
condition and by the relationship between score change and the physician's
assessment of clinical outcome. This study demonstrated that the MYMOP is
a valid and potentially useful instrument for the assessment of patient out
comes in acute exacerbations of chronic bronchitis and is more responsive t
han the MOS-6A or EQ-5D in this setting. The choice of instrument will vary
according to the objective of the study.