Primary gastric lymphoma with spontaneous perforation is rare. We report he
rein the case of a 53-year-old-man who was admitted to our hospital with se
vere epigastralgia. Emergency endoscopic examination showed a perforated ga
stric tumor in the lower body of the greater curvature, and a distal subtot
al gastrectomy with lymph node dissection was performed. The resected tumor
measured 10.0 x 8.0 cm and was associated with an area of ulceration, 8.0
x 6.0 cm in size, and perforation, 1.0 x 0.5 cm in size. Pathological exami
nation confirmed a diagnosis of B-cell malignant lymphoma of the diffuse, m
edium-sized cell type. According to the Ann Arbor and Naqvi classifications
, the lymphoma was stage II and stage III, respectively. Postoperative adju
vant chemotherapy comprising cyclophosphamide, doxorubicin, vincristine, an
d prednisolone (CHOP) was given. The patient is currently well with no sign
s of recurrence, 2 years 4 months after his operation.