Bioconversion of substituted styrenes to the corresponding enantiomerically pure epoxides by a recombinant Escherichia coli strain

Authors
Bernasconi, S Orsini, F Sello, G Colmegna, A Galli, E Bestetti, G
Citation
S. Bernasconi et al., Bioconversion of substituted styrenes to the corresponding enantiomerically pure epoxides by a recombinant Escherichia coli strain, TETRAHEDR L, 41(47), 2000, pp. 9157-9161
Citations number
8
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
47
Year of publication
2000
Pages
9157 - 9161
Database
ISI
SICI code
0040-4039(20001118)41:47<9157:BOSSTT>2.0.ZU;2-6
Abstract
Enantiomerically pure epoxides are produced by bioconversion of the corresp onding styrenes using a recombinant Escherichia coli strain containing the styrene monooxygenase gene cloned from Pseudomonas fluorescens ST. Differen t procedures were used to optimise yields and to permit product isolation. Conversion rates depend on the position and nature of the styrene substitue nt. (C) 2000 Elsevier Science Ltd. All rights reserved.