Sequential alkylation/transition metal catalysed annulation reactions of 1,3-dicarbonyl compounds with propargyl bromide

Authors
Arcadi, A Cerichelli, G Chiarini, M Di Giuseppe, S Marinelli, F
Citation
A. Arcadi et al., Sequential alkylation/transition metal catalysed annulation reactions of 1,3-dicarbonyl compounds with propargyl bromide, TETRAHEDR L, 41(47), 2000, pp. 9195-9198
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
47
Year of publication
2000
Pages
9195 - 9198
Database
ISI
SICI code
0040-4039(20001118)41:47<9195:SAMCAR>2.0.ZU;2-Q
Abstract
beta -Diketones, beta -ketoesters and beta -ketonitriles in the presence of propargyl bromide, DBU and a catalytic amount of CuI in toluene give 2,3,5 -trisubstituted furans through sequential alkylation/cyclisation/isomerisat ion reactions. (C) 2000 Elsevier Science Ltd. All rights reserved.