alpha,beta-Differentiated tandem diamination of cinnamic esters using N,N-dichloro-2-nitrobenzenesulfonamide and acetonitrile as the nitrogen sources

Authors
Li, GG Kim, SH Wei, HX
Citation
Gg. Li et al., alpha,beta-Differentiated tandem diamination of cinnamic esters using N,N-dichloro-2-nitrobenzenesulfonamide and acetonitrile as the nitrogen sources, TETRAHEDR L, 41(45), 2000, pp. 8699-8703
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
45
Year of publication
2000
Pages
8699 - 8703
Database
ISI
SICI code
0040-4039(20001104)41:45<8699:ATDOCE>2.0.ZU;2-A
Abstract
Tandem diamination of cinnamic esters provides a new approach to anti alkyl N alpha-(2-Ns), N beta -Ac diaminophenylpropionates. The new reaction proc eeds to completion within 3 hours at room temperature using N,N-dichloro-2- nitrobenzenesulfonamide (2-NsNCl(2)) as the nitrogen source in acetonitrile , which is also involved in the reaction process. Seven diamine derivatives have been obtained with good yields and stereoselectivity. (C) 2000 Elsevi er Science Ltd. All rights reserved.