Citation
A. Goswami et al., Microbial reduction of omega-bromoacetophenones in the presence of surfactants, TETRAHEDR-A, 11(18), 2000, pp. 3701-3709
Citations number
34
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166
→ ACNP
Volume
11
Issue
18
Year of publication
2000
Pages
3701 - 3709
Database
ISI
SICI code
0957-4166(20000922)11:18<3701:MROOIT>2.0.ZU;2-U
Abstract
Several omega -bromoacetophenone derivatives 6a-f were reduced to (R)-(-)-2
-bromo-1-(phenyl/substituted phenyl) ethanol derivatives 7a-f with whole ce
ll biocatalysts in good yields. The enantiomeric excesses were increased to
95% using an anionic surfactant under an inert atmosphere in an aqueous me
dium. (C) 2000 Elsevier Science Ltd. All rights reserved.