Eukaryotic DNA primase

Eukaryotic DNA primase initiates the synthesis of all new DNA strands by sy nthesizing short RNA oligomers on single-stranded DNA, Additionally, primas e helps couple replication and repair and is critical for telomere maintena nce and, therefore, chromosome stability. in light of the many aspects of D NA metabolism in which primase is involved, understanding the unique featur es of the mechanism of this enzyme and how it interacts with other proteins will greatly advance our knowledge of DNA replication and repair.