Aim: We analysed factors influencing diagnostic yield and treatment and the
ir potential for optimising the use of carotid duplex sonography (CDS).
Method: Patients referred for CDS were divided into three groups: 1: high l
ikelihood of carotid symptoms, 2: suspected presence of asymptomatic caroti
d lesions, 3: other indications. Clinical data, the grading of stenosis and
the therapeutic consequences were analysed. The efficiency of diagnosis wa
s tested with an algorithm.
Results: 344 patients were included, Groups 1, 2 and 3 contained greater th
an or equal to 1 pathological finding in the carotid or vertebral system in
68 %, 86 % and 55% respectively, whereas high-grade stenoses or occlusions
of the internal carotid artery (ICA) were detected in 10.8%, 16% and 3.6 %
respectively. Age > 50, > 1 risk factor, carotid murmur and concomitant va
scular disease were associated with a significantly higher diagnostic yield
. Subsequent treatment in groups 1, 2 and 3 involved carotid thromboendarte
rectomy in 6.4%, 2% and 0.7% respectively and the start of treatment with a
platelet aggregation inhibitor in 9%, 30% and 17% respectively. The optimi
sation algorithm would have saved 21 % of CDS scans.
Conclusion: Clinical pre-selection criteria determine the diagnostic yield
of CDS. The potential for optimisation depends on the treatment regimen cho
sen for asymptomatic stenoses and secondary prophylaxis.