Identification and sequence analysis of the core protein genes of bovine adenovirus 2

The DNA sequence of the genome of bovine adenovirus type 2 (BAdV-2) was det ermined between map units 42.5 and 50. By sequence analysis and homology se arch, the genes of five structural proteins were identified within this reg ion: the penton base protein (III; partial sequence), the major core protei n precursor (pVII), the minor core protein (V), the mu core protein precurs or (pX) and the hexon associated protein precursor (pVI; partial sequence). The putative polypeptides were compared to their known counterparts from o ther adenoviruses. The existence of protein V and the presence and structur e of certain protease cleavage recognition sites confirmed BAdV-2 as a memb er of the genus Mastadenovirus. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.