Focal lesions in cirrhotic liver: Comparing MR imaging during arterial portography with gd-enhanced dynamic MR imaging

The purpose of this study was to document the additional value of MR imagin g during arterial portography (MRAP) in patients examined with intravenous contrast-enhanced dynamic MR imaging for the assessment of focal lesions in patients with cirrhosis or chronic viral hepatitis. The MR images of 24 pa tients with 39 hepatocellular carcinomas and 18 benign hepatocellular nodul es examined with dynamic MR imaging and MRAP within a Iri-day interval were retrospectively reviewed. For 39 hepatocellular carcinomas, MRAP revealed 37 perfusion defects (95%), while dynamic MR imaging demonstrated 35 occurr ences of nodular contrast-enhancement (90%) on arterial dominant phases. Am ong the ii benign nodules misinterpreted as hepatocellular carcinoma due to their high signal intensities on arterial-dominant phases of dynamic MR im aging, eight (73%) showed intratumoral portal venous perfusion on MRAP and were regarded as benign nodules. As a result of its high sensitivity and it s potential ability to enable differentiation of benign and malignant hepat ocellular nodules, MRAP can be added to dynamic MR imaging for planning fut ure management in patients with equivocal hepatocellular nodules in the cir rhotic liver.