Filiform polyposis of the colon in chronic inflammatory bowel disease (so-called giant inflammatory polyps)

On the basis of 3 of our own cases, we describe unusually intense forms of filiform polyposis and local giant polyposis as a consequence of chronic in flammatory bowel disease. The patients are: A 52-year-old woman who for 7 y ears has been known to have Crohn's disease (CD); a 55-year-old man who for 14 years has been known to have chronic inflammatory bower disease, which was first thought to have been ulcerative colitis, but, as a result of the findings on the subtotal colectomy specimen, had to be classified as Crohn' s disease or colitis indeterminate: and a 53-year-old woman known to have h ad ulcerative colitis for 37 years. From the literature on the subject, we drew up a chronological list of a total of 43 cases with similar or complet ely identical findings. The clinical significance of the findings in their particularly massive intensity results from their necessary differentiation - in the context of differential diagnosis - from a malignant tumor, in pa rticular from a carcinoma in association with chronic inflammatory bowel di sease, or from a villous adenoma. The indication of a need to operate results from the impossibility of being able definitely to rule out a malignant degeneration by means of clinical methods. Also, experience shows that with massive findings of the kind desc ribed a spontaneous disappearance cannot be expected. Finally, too, the cli nical symptoms and the patients subjective complaints necessitate balanced surgical treatment, taking into consideration the site and the extent of th e lesion.