Synthesis and complexation of spacer modified phosphorylated glucose derivatives

Authors
Siedentop, T Neda, I Schmutzler, R
Citation
T. Siedentop et al., Synthesis and complexation of spacer modified phosphorylated glucose derivatives, Z NATURFO B, 55(10), 2000, pp. 956-960
Citations number
19
Categorie Soggetti
Chemistry
Journal title
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
ISSN journal
09320776 → ACNP
Volume
55
Issue
10
Year of publication
2000
Pages
956 - 960
Database
ISI
SICI code
0932-0776(200010)55:10<956:SACOSM>2.0.ZU;2-Y
Abstract
Treatment of the spacer modified glucose derivative 1 with diethylaminotrim ethylsilane furnished the bis-silylated molecule 2. Reaction of 2 with two equivalents of the phosphorus compounds 3, 4, and 5 led to the spacer phosp horylated glucosyl derivatives 6, 7 and 8. Complexation of 6 with (COD)PtCl 2 gave complex 9; the cis-conformation of 9 could be confirmed by P-31 NMR investigations.