An approach to multi-copy search in molecular replacement

Authors
Vagin, A Teplyakov, A
Citation
A. Vagin et A. Teplyakov, An approach to multi-copy search in molecular replacement, ACT CRYST D, 56, 2000, pp. 1622-1624
Citations number
15
Categorie Soggetti
Chemistry & Analysis
Journal title
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
ISSN journal
09074449 → ACNP
Volume
56
Year of publication
2000
Part
12
Pages
1622 - 1624
Database
ISI
SICI code
0907-4449(200012)56:<1622:AATMSI>2.0.ZU;2-A
Abstract
The molecular-replacement method has been extended to a simultaneous search for multiple copies of the macromolecule in the unit cell. The central poi nt of this approach is the construction of a multi-copy search model from t he properly oriented monomers using a special translation function. The mul ti-copy search method has been implemented in the program MOLREP and succes sfully tested using experimental data.