Crystallization of the catalytic domain of murine terminal deoxynucleotidyl transferase

Authors
Sukumar, N Boule, JB Expert-Bezancon, N Jourdan, N Lescar, J Rougeon, F Papanicolaou, C Delarue, M
Citation
N. Sukumar et al., Crystallization of the catalytic domain of murine terminal deoxynucleotidyl transferase, ACT CRYST D, 56, 2000, pp. 1662-1664
Citations number
26
Categorie Soggetti
Chemistry & Analysis
Journal title
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
ISSN journal
09074449 → ACNP
Volume
56
Year of publication
2000
Part
12
Pages
1662 - 1664
Database
ISI
SICI code
0907-4449(200012)56:<1662:COTCDO>2.0.ZU;2-I
Abstract
The catalytic domain of murine terminal deoxynucleotidyl transferase (TdT) has been crystallized in the space group P2(1)2(1)2(1), with unit-cell para meters a = 47.1, b = 86.2, c = 111.7 Angstrom. The crystals diffract to a r esolution of 2.4 Angstrom using synchrotron radiation and a full data set h as been collected from the native crystals. The enzyme was shown to be acti ve in the crystalline state.